Instead, fresh diethyl ether is added to the aqueous layer, since it has the potential to extract more compound. One of the reasons why SPE is a suitable technique for this analysis is the fact that there should be higher recoveries (% recoveries)since both caffeine and theophylline are polar compounds, with theophylline being more polar than caffeine which tells us that caffeine will have the longer retention time than theophylline. In addition to determining whether a substance is polar or nonpolar, we can also measure how much polarity it has. However, the chromatogram shows that caffeine has a longer retention time than acetaminophen?? Goli Energy Bites are made with caffeine, guarana extract, vitamins B6, B9, & B12 to help Support Cellular Energy Production, Support a Healthy Heart, Provide Essential Nutrients, Support a Healthy Nervous System, Support a Healthy Immune System and so much more. Paracetamol is sparingly soluble in water. Is Ibuprofen Polar Or Non-Polar Ibuprofen, also known as Motrin or Advil, is a medication used to relieve pain, inflammation, and fever. In this article, we have satisfied your query that caffeine is more polar than aspirin and have explored the properties of caffeine and aspirin, including their polarity and solubility, to show why caffeine in some instances actually makes for a better painkiller than aspirin does! \[4.07 = \dfrac{\left( \dfrac{x}{150 \: \text{mL ether}} \right)}{\left( \dfrac{0.50 \: \text{g} - x}{150 \: \text{mL water}} \right)}\]. Between caffeine, acetaminophen, aspirin, and ibuprofen, which is the The LibreTexts libraries arePowered by NICE CXone Expertand are supported by the Department of Education Open Textbook Pilot Project, the UC Davis Office of the Provost, the UC Davis Library, the California State University Affordable Learning Solutions Program, and Merlot. 2. Solubility data for caffeine is shown in Table 4.2. Who makes the plaid blue coat Jesse stone wears in Sea Change? The Oxygen and Nitrogen molecules have a stronger polarity than Carbon, allowing them to slightly pull the electrons towards them in their covalent bond.