McCarthy CP The AMI cutoff concentration is determined by ROC analysis of results from marker concentrations collected within the established diagnostic window on a population of consecutive chest pain patients presenting to the ED for AMI rule-out. What is the highest troponin level ever recorded? 1 and Table1(14, 7, 1320,). , Roberts R Cardiac troponin: an emerging cardiac biomarker in Troponin Some of these approaches consider the continuum of baseline concentrations and deltas, which might be a more informative and personalized approach (52,). All authors confirmed they have contributed to the intellectual content of this paper and have met the following 4 requirements: (a) significant contributions to the conception and design, acquisition of data, or analysis and interpretation of data; (b) drafting or revising the article for intellectual content; (c) final approval of the published article; and (d) agreement to be accountable for all aspects of the article thus ensuring that questions related to the accuracy or integrity of any part of the article are appropriately investigated and resolved. Recently, a qualitative cage-side ELISA (SNAP Feline proBNP) was introduced, which allows for rapid determination of feline NT-proBNP concentration. Very low concentrations using high-sensitivity-cTn (hs-cTn) assays, with small to no delta, have high sensitivity and negative predictive value to exclude MI. Recently cTnI has been shown to be increased in dogs and cats with cardiomyopathies, and this biomarker may have some value as a screening test for hypertrophic cardiomyopathy (HCM) in cats. Sandoval Y However, the diagnosis of acute MI is dichotomous, and not equivalent to risk stratification. However, they have not been found to be reliable, independent predictors of adverse cardiac outcomes in dogs or cats with heart disease.
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